Editorials LBS Knowledge Pathway Menu Knowledge Pathway Editoriale Case study Interviste, domande e risposte Risorse formative Tutorial Webinar Pathologist Pathway Process of Fixation and the Nature of Fixatives Geoffrey Rolls , BAppSc, FAIMS Fixation is a critical step in the preparation of histological sections. If it is not carried out under optimal conditions or if fixation is delayed, a tissue specimen can be irreversibly damaged. No matter how much care is subsequently taken in tissue... Approach Angle in Stereotaxic Surgery Charles W. Scouten , Ph.D. Varying the approach angle in stereotaxic surgery can overcome the conflict between positional accuracy and interpretability. Fortunately, modern computer controlled stereotaxic instruments make this possible. Fixation and Fixatives (3) – Fixing Agents Other than the Common Aldehydes Geoffrey Rolls , BAppSc, FAIMS As well as formaldehyde and glutaraldehyde, discussed previously, a number of other reagents have been used for fixation, sometimes in simple solution but often combined with other agents in the form of compound fixatives. The more important of these are... Freezing Biological Samples Miles Cunningham Neuroscience researchers usually need to see slices of whole brain in order to determine the location in brain of detail they are viewing under the microscope. Fixation and Fixatives (2) – Factors Influencing Chemical Fixation, Formaldehyde and Glutaraldehyde Geoffrey Rolls , BAppSc, FAIMS This second part of the Fixation and Fixatives series covers the factors that influence the rate and effectiveness of tissue fixation as well as looking at two common fixatives: formaldehyde (histology) and glutaraldehyde (ultrastructural electron microscopy... Specimen Tracking Systems: Tracking Samples Helps Reduce Misdiagnosis Mikko Rasanen , Senior Product Manager Sample tracking systems help reduce misdiagnosis by positively identifying patient tissue throughout the diagnostic process. Stereotaxic Accuracy Charles W. Scouten , Ph.D. The instrument for moving a probe to a given coordinate in space – inside the brain – is a stereotaxic instrument. Effects of Fixation and Tissue Processing on Immunocytochemistry Peter Jackson The foundation of all good histological preparations is adequate fixation and good tissue processing. Pagination « Previous Page 1 Current page 2 Want us to feature your writing? We are looking for more great writers to feature here. Send us a submission and we’ll be in touch! Send your writing! Like what you see? Get more Knowledge Pathway content delivered directly to your inbox. Unsubscribe at any time. Subscribe today!