Home • Clinical Solutions • Case Studies • Case Base Versus Single Piece IHC Workflows Evaluated in a Large Reference Laboratory RELATED PRODUCTS BOND-III Fully Automated IHC and ISH Staining System Case Base Versus Single Piece IHC Workflows Evaluated in a Large Reference Laboratory The Leica Biosystems Process and Solutions Optimization team has partnered with a high-volume reference laboratory to evaluate the potential impact of a case based IHC workflow versus an individual slide workflow. The Leica Biosystems team observed current IHC protocols, staining instrument utilization, and case completion process. This reference laboratory performed 122,733 IHC stains utilizing 2 different staining systems. System 1 included 7 IHC stainers with random access slide capability and System 2 contained 3 stainers with 3, 10-slide racks. Currently, 22 steps, including 2 manual processes are required to complete the IHC staining procedure in System 1. By completing a time and motion study, the Leica Biosystems Process & Solutions Optimization team determined signifi cant LEAN laboratory savings of time, overproduction, and talent. By evaluating both instrument workfl ows, significant manual sorting times were observed, and data analysis identified the following: Total sorting times for fi lling both instruments averaged 4 minutes, 24 seconds for System 1 and 1 minute, 32 seconds for System 2. Total of 5 minutes, 56 seconds combined per run. Image Fig 1(Above) : Current Average Sort Time Time studies further revealed a manual slide rinse and counterstain process specifi c to System 1. By eliminating manual sorting, counterstaining, and slide rinsing with System 2’s case-based approach, appropriate instrumentation utilization can yield substantial improvements in time savings, hand-on time, and touchpoints. Current hands-on time for System 1: Individual slide staining process totals 89.8 seconds per slide, totaling 3059 hours per year. Image Fig 2(Above) : Hands On Time Comparison Proposed hands-on time for System 2: Case base model reduces total hands on time to 28.2 seconds per slide, totaling 961 total hours per year a 69% difference between current and proposed staining processes. Image Fig 3(Above) : 69% reduction in hands-on time Projections and Realized Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions. Leica Biosystems content is subject to the Leica Biosystems website terms of use, available at: Legal Notice. The content, including webinars, training presentations and related materials is intended to provide general information regarding particular subjects of interest to health care professionals and is not intended to be, and should not be construed as, medical, regulatory or legal advice. The views and opinions expressed in any third-party content reflect the personal views and opinions of the speaker(s)/author(s) and do not necessarily represent or reflect the views or opinions of Leica Biosystems, its employees or agents. Any links contained in the content which provides access to third party resources or content is provided for convenience only. For the use of any product, the applicable product documentation, including information guides, inserts and operation manuals should be consulted. Copyright © 2024 Leica Biosystems division of Leica Microsystems, Inc. and its Leica Biosystems affiliates. All rights reserved. LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH. Contact Our Clinical Expert Now If you have viewed this educational webinar or training and would like to apply for continuing education credits with your certifying organization, please download the form to assist you in adding self-reported educational credits to your transcript. Apply for self-reported educational credits SHARE Facebook Twitter LinkedIn Email
The Leica Biosystems Process and Solutions Optimization team has partnered with a high-volume reference laboratory to evaluate the potential impact of a case based IHC workflow versus an individual slide workflow.
